Study of effectiveness of enrofloxacin and moxifloxacin in experimental salmonellosis of chickens

In this publication we present a comparative study of effectiveness enrofloxacin and moxifloxacin for treatment chickens, experimentally infected with Salmonella infantis . The chickens received both drugs in water-soluble form via drinking water ad libitum at concentrations 200 mg/L, 100 50 mg/L 25 one day before the challenge then four consecutive days. were challenged by intraperitoneal injection 150 million CFUs one-day old agar culture S. 0.5 mL isotonic saline. observation period was 15 Enrofloxacin proved most effective (88% 84%) mg/L. Lower caused decrease its effectiveness. When administered concentration survival rate 64%. our experiment considerably lower. receiving respectively 32%, 28%, 32% 16%, their average lifespan half as long those groups, enrofloxacin. results research prove high experimental salmonellosis chickens.